Main

Substantial efforts over the past century to reduce childhood mortality and adult morbidity raised global life expectancy at birth from ~30 years in 1900 to more than 72 years today, signifying remarkable improvement in human well-being1,2. Meanwhile, decreasing fertility has contributed to population aging in many countries throughout the world. The share of the older population (65 years or over) increased from 6% to 9% in the past 3 decades and is projected to climb to 16% in the next 3 decades3. Increasing longevity amid rapid global urbanization poses outstanding challenges to societies in the development and planning of cities and communities, ranging from health service issues and social participation to ensuring that growing numbers of older citizens have safe and easy access to buildings, public infrastructures, and a range of ambient physical environments.

In general, societal responses to rising longevity aim to mitigate and adapt to the unexpected challenges brought by an increasing older population. Since the initial guidelines released by the World Health Organization (WHO) in 2007 (ref. 4), numerous policies and initiatives have been proposed to create age-friendly cities and communities worldwide that would foster active and healthy aging5,6,7 (see definitions in Box 1). The WHO’s framework for age-friendly cities focuses on eight interconnected domains (Fig. 1) that encompass the urban physical environment, social environment, and municipal services4. This influential framework has raised wide awareness of and interest in population aging in urban planning and management8,9, and at least half of the WHO Member States and thousands of cities and communities participate in related programs10,11.

Fig. 1: Eight interconnected domains of the WHO’s age-friendly cities framework.
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These domains reflect different aspects of urban physical environments, social environments, culture, and health and social services. Adapted from ref. 4.

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Despite these encouraging achievements globally, the age-friendly cities framework has also been criticized for the inadequacy of the eight domains and the lack of measurability of ‘age-friendliness’8,11. Moreover, while some age-friendly initiatives acknowledge in their missions and targets that age-friendly cities should go beyond being ‘elderly friendly’ by being friendly to people of all ages (Box 2), there is only modest evidence that they do so. This seemingly paradoxical trend is common in most age-friendly initiatives: actions and design principles in these initiatives, including WHO’s guidelines, focus largely on older populations6,8. The WHO Global Database of Age-friendly Practices12, for example, documents 376 actions in more than 200 cities and communities globally (as of May 2021), yet more than 79% of them mainly target older adults. Despite language and sentiment that acknowledges needs across the life course, the main focus of age-friendly cities is on creating urban environments that are accessible and responsive to older people.

However, a growing body of evidence has shown that healthy and successful aging (Box 1) is strongly influenced by numerous factors throughout life. From a life-course perspective, attention has been focused on lifestyle factors, such as diet and physical activity13,14; socioeconomic determinants, such as education, financial status, and social support15,16; and, increasingly, the characteristics of physical environments, such as green spaces and air quality17,18,19. In particular, continuous interactions with and cumulative exposures to the surrounding physical and social environments throughout life have vital roles in later-life outcomes. Therefore, designing and planning cities with responsive actions that largely or even exclusively focus on older persons, as is the case for most age-friendly actions, is insufficient.

For a population that is living four decades longer than the population a century ago, governments and societies have unique opportunities to intentionally plan from the moment children are born, instead of mitigating and adapting to the consequences by the time they reach old age. To better prepare people for sustainable, century-long lives in future cities, we need to shift from traditional age-friendly cities, which primarily focus on older people, to longevity-ready cities, a concept that extends the framework for age-friendly cities to further consider the cumulative effects (Box 1) of the urban environment from a life-course perspective in urban planning and design. Although the urban social environment could be equally important, in this Perspective we mainly focus on the urban physical environment.

Influence of the urban physical environment on healthy longevity begins long before older age

The survival and health of older people living in urban settings are substantially influenced by various components of ambient physical environments, as has been underscored by numerous epidemiological studies20,21,22,23. Nevertheless, environmental influences on aging begin long before older age (Fig. 2). For example, many chronic diseases in later life, including cognitive decline and dementia, can result from persistent exposure to airborne toxins in the outdoor urban environment emitted from traffic and industrial activities20,24. In fact, the rate of biological aging and chronic degenerative disease risk can be traced to environmental exposures in early childhood, even prenatal and neonatal stages, key stages of physical, cognitive, and emotional development. Several pregnancy outcomes can be influenced by ambient air pollution: maternal exposure to common urban airborne pollutants (such as PM2.5, PM10, CO and NO2) is associated with low birth weight and premature birth25,26, which often have long-term effects that include lower muscle strength27 and higher risks of chronic noncommunicable diseases (for example, cardiometabolic and glucose metabolism disorders) in adulthood and later life28. Furthermore, in utero and postnatal exposures to airborne toxins can alter lung structure and function, leading to increased risks of asthma and other chronic respiratory diseases in childhood and adulthood, and ultimately functioning in later life29,30.

Fig. 2: Examples of factors (see definitions in Box 1) in the urban physical environment and their potential long-term impacts on healthy longevity throughout life.
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The four examples of physical environmental components shown here are air pollutants, drinking contaminated water, heat stress, and access to green spaces. Health outcomes may be promoted or hindered across several life stages (for example, access to green spaces may promote physical and social activities for all life stages). Dashed lines represent statistical or causal relationships suggested by multiple lines of evidence (see main text).

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Adverse long-term impacts of air pollutants also arise indoors, where urban residents spend most of their time31. Indoor air quality is influenced by possible emissions from indoor combustion appliances and smoking and the air exchange with the outdoor environment. Especially, household air pollution emitted from solid fuel combustion (for example, coal, wood, and charcoal for cooking and heating) is among the leading risk factors for global attributable disability-adjusted life-years32, despite the substantially improved air quality in many countries. Other contaminants, such as formaldehyde, benzene, and lead, that are released from building materials and furnishings also have long-lasting, harmful effects on healthy aging and longevity33. As shown in epigenetic studies, exposure to airborne pollutants (both indoor and outdoor) during early-life stages may induce placental and newborn telomere shortening and accelerated biological aging26,34. The association between shorter telomere length and higher air-pollution exposure has been observed among children, young adults, and older adults35,36,37, and may further increase the risks of some age-related diseases38. In addition, exposure to secondhand smoke can delay neurodevelopment in children and adolescents and lead to poor academic achievement18,39. Moreover, higher air-pollution exposure for adults is associated with accelerated aging of the brain and arteries, faster cognitive decline, and higher risks of dementia, impairing later-life decision-making in ways that extend beyond physical health, such as decisions about financial matters18,24,40,41.

Likewise, chemical and microbial contaminants in municipal tap-water systems adversely influence people of all ages and exert short- and long-term toxic effects on healthy longevity42 (Box 1). Exposure to these contaminants is mainly attributable to poor sanitation and the lack of access to clean water in many cities in low-income and some middle-income countries, whereas in high-income countries it sometimes arises from aging urban water infrastructures. High-level prenatal and childhood exposure to arsenic through water is consistently associated with increased risks of cardiovascular diseases, pulmonary function impairment, respiratory diseases, and cancers in adulthood and later life43,44. Early-life exposures to lead in drinking water (from lead-bearing plumbing) can harm neuropsychological development, leading to many cognitive and neurobehavioral issues in subsequent life stages45,46. Similarly, lifelong fluoride exposure may increase the risk of bone fractures in older adults, substantially affecting mobility and later-life quality47.

The thermal environment is another critical component of the urban physical environment that has long-lasting effects on healthy longevity. Both extremely hot and cold weather can be life-threatening to people of all ages, although young children, older people, and those with chronic medical conditions are more vulnerable22,48. Cities may further alter the impacts of background weather conditions on public health49. For instance, the urban heat island effect often increases outdoor temperature, intensifies heat stress, and eventually exposes inhabitants to higher risks of heat-related diseases and deaths50; by contrast, green spaces, water features, and shading infrastructure may effectively alleviate outdoor heat stress51. Indoor temperature is mainly controlled by available cooling and heating systems and building insulation. Buildings with limited access to cooling systems can exacerbate indoor heat stress in summers and trigger heatstroke and heart failure, whereas poorly insulated homes without effective heating systems in cold seasons can increase the risk of respiratory infection and cardiovascular diseases, all reducing the chance of survival to age 65 and older33,48,52. As shown in epidemiological surveys, survivors from heatstroke may experience permanent damage and lasting neurological sequelae (for example, functional impairment) with increased risks of mortality53,54.

Green spaces, such as parks and gardens, are commonly used in cities as recreational areas to enhance environmental quality and to promote public health. Many studies have observed strong associations between increased urban green spaces and reduced risks of various chronic diseases (for example, respiratory and cardiovascular diseases) across the lifetime55. This is partly because, compared to unshaded, impervious surfaces, well-designed urban green spaces can reduce outdoor temperatures on hot days and absorb and filter some air pollutants, directly contributing to improved thermal comfort and air quality56. Additionally, access to improved urban green spaces may promote physical activity and social interactions, benefiting both physical and mental health throughout life17,57,58. Urban green spaces also have an important role in influencing cognitive functions. Contact with green spaces in childhood can enhance working memory, attentiveness, and cognitive development59, and a higher level of access to green spaces during both childhood and adulthood may stave off later-life cognitive decline and contribute to more successful cognitive aging17.

As noted above, many components of the urban physical environment start impacting inhabitants in utero and continue throughout life, eventually affecting life quality at older age. In addition to pollutants and thermal stress, human exposure to many other urban environmental factors (for example, traffic conditions, noise, or access to parks) is closely related to the design and maintenance of buildings, planning of roads and transportation infrastructure, and physical structures of cities and neighborhoods, the influence of which can last a lifetime20,60,61. For instance, planning interventions that encourage walking, cycling, and the use of public transit in some cities can promote physical activity in all ages and effectively reduce the burden of disease and traffic-related injuries62. In particular, there is arguably no better prescription for healthy aging than exercise, and even walking is greatly influenced by neighborhood features such as sidewalks and streetlights63. Moreover, close and inevitable interactions between urban physical and social environments cumulatively shape human behavior and social activity/engagement, and exert far-reaching impacts on cognitive functioning and neurological outcomes throughout life64.

Designing the urban physical environment for longevity from a life-course perspective

Distinct from most age-friendly city initiatives, longevity-ready cities acknowledge the cumulative effects of exposures to the ambient urban environment. Recently, attention has been devoted to the early-life social determinants of healthy and successful aging, such as social and professional networks65. Meanwhile, some existing urban-planning regulations, national/state standards, and initiatives (for example, the WHO’s Healthy Cities initiative66) have benefited the health of the general population by improving the quality of the urban physical environment. Nevertheless, the cumulative impacts of the urban physical environment on active and healthy aging are still largely overlooked. From a life-course perspective, longevity-oriented urban-design strategies and policies are imperative so that cities will be ready for an increasing population of individuals who are living longer. Here, we review several urban-planning examples that can potentially foster healthy longevity through improved physical environmental designs. These examples move beyond the common older-person-focused, age-friendly model, and are similar to or at least partly consistent with the longevity-ready concept.

The first example is the Community for All Ages initiative developed by the Mid-America Regional Council in the Kansas City metropolitan area. In response to increasing diverse populations in this region, the initiative aims to help city planners to identify measures to improve the life quality of residents beyond older people67. It outlines criteria and strategies that can be used in policy development and implementation for both physical and social environments. This initiative also focuses on bottom-up engagement of residents through discussion forums, workshops, and public-awareness campaigns, and has been financially supported by several regional and national organizations. Along with this initiative, a recognition program has been developed to encourage cities and communities to take steps from identifying present issues to adopting the Community for All Ages plans. Nearly 20 cities and communities in this region have either initiated or implemented related actions. Several cities and communities have adopted proactive strategies for the urban physical environment, including sustainable land-use development and regulations, promotion of housing adaptability, and designs of effective public transit and walkable neighborhoods to meet the needs of multiple generations.

Another example is a suite of policies and actions by the Atlanta Regional Commission (ARC) in the Atlanta metropolitan area. The ARC has developed a holistic, long-range regional plan with the goal of improving urban infrastructure, fostering healthy and livable communities, and building a robust and competitive economy68. Several programs and initiatives, including the Lifelong Communities and Livable Centers Initiative, have provided financial resources and guidelines to communities to increase access to green spaces and other services, improve the safety of sidewalks and intersections, and eventually remove existing obstacles to aging in place. In particular, along with large-scale plans, such as transportation improvement and building renovations, multiple Lifelong Communities sites have implemented more visible and rapid projects, including farmers markets and community gardens, to sustain and enhance community engagement. Recognizing that longevity is determined by a combination of physical environmental factors, physical- and mental-health factors, and socioeconomic factors, the ARC recently launched a 5-year Live Beyond Expectations Regional Strategic Plan on aging69. This ambitious plan aims to use research to identify the key drivers of current life-expectancy disparities in this region, and to develop and execute strategies to close life-span gaps, while raising public awareness of life-expectancy determinants and inequities.

More recently, California released the Master Plan for Aging (MPA), a 10-year concerted blueprint for state agencies, multilevel governments, the private sector, and philanthropic organizations70. For a state in which the proportion of the population over age 60 is projected to increase to more than one-quarter by 2030, this master plan seeks to ensure that all people can thrive throughout all life stages, and to promote healthy and equitable aging (Box 1). As stated in the plan, the MPA is not simply for the current older population, but rather is a blueprint for aging across the entire life course, acknowledging the role of different life stages in reducing disparities in life expectancy. In particular, the MPA’s first goal, Housing for All Ages and Stages, is closely related to the concept of longevity-ready cities. It includes strategies to increase affordable and safe housing options with improved community walkability, safe public transportation, convenient access to parks and other community spaces, and strong climate and disaster preparedness.

There are also plans and initiatives related to urban physical environmental designs in other countries that can potentially benefit residents from a life-course perspective, including the concept of Lifetime Neighbourhoods in the UK71, the All-Age-Friendly City project in the UK72, and the compact city planning in Toyama, Japan73. In general, the design of longevity-ready cities should be multiscaled and should target various key aspects of the physical environment that cumulatively influence healthy longevity, for example by residential and commercial building retrofits, making modifications to building and community standards, replacing municipal water-distribution systems, developing walkable neighborhoods, redesigning public space and transportation systems, and introducing city-scale zoning regulations and land-use planning, among other steps. Although they have different objectives, similarities between longevity-ready urban designs and some city-wide sustainability plans signify the potential for integrating policies and optimizing financial investments and expenses.

Longevity-ready cities in a changing climate

The cumulative impact of the urban physical environment on active and healthy aging is not static. In fact, it will probably change with environmental factors that are influenced by climate change74,75. Cities in a warmer future are projected to experience increasing risks of individual and compound climate and weather extremes, such as more frequent heat waves, sea-level rise and coastal flooding, and intensified wildfire activities and associated air-pollution episodes76. These projected future changes, amid continuous global urbanization, can directly increase disaster-related mortality and morbidity, and indirectly exacerbate burdens of vector-borne disease outbreaks and mental illness, threatening the healthy longevity of not only older people, but urban inhabitants of all ages75. Future demographic changes in many countries could further amplify the negative impacts on longevity. For example, the exposure to unprecedented heat is projected to intensify in many countries owing to aging of their populations, despite the potential decrease in total population77. Nevertheless, existing age-friendly actions and practices often overlook these dynamic changes. From a life-course perspective, the design of urban physical environments for healthy, longer lives in the upcoming decades naturally calls for proactive actions to mitigate and adapt to climate change.

In response to increasing heat stress, urban heat-mitigation measures and adaptive social strategies need to be judiciously selected in different cities and informed by existing urban structure and composition, changing demographics, and local urban climate characteristics. Public infrastructure and housing units at increasing risks for future flooding (due to extreme rainfall events, hurricanes, or sea-level rise), especially those designed to support vulnerable populations and aging in place, require redesign and renovation months or years prior to potential disasters to improve their resistance78. Proactive and dynamic land-use planning and landscape design (for example, residential landscape and evacuation zones) close to or located at the wildland–urban interface79 should be implemented to reduce the impact of future risks related to mortality and morbidity posed by wildfire and smoke. Interventions tailored to local conditions and projected future changes of climate and populations, such as early warning systems80, will enhance the preparedness and resilience of longer-lived populations when they confront future extremes and disasters. Planning for climate and weather extremes years or even decades in advance will better position cities to embrace the upcoming waves of aging and promote healthy longevity. Note that, although we focus herein on urban physical environments, bidirectional influences between physical structures and social interactions also powerfully impact factors linked to healthy aging during extreme events81, ranging from the proximity of available helpers to the dire consequences of social isolation.

Of course, strategy implementation always demands weighing potential tradeoffs. Planning for longevity-ready cities requires a holistic consideration of how mitigation and adaptation strategies implemented in the urban physical environment might negatively affect the healthy longevity of urban residents. However, both age-friendly city initiatives and general urban planning have often failed to consider these unintended consequences. For example, despite its efficacy in cooling the environment and absorbing pollutants, urban vegetation also emits volatile organic compounds and pollen and can reduce the mixing of air56. As a result, greening cities without carefully examining vegetation species and arrangement may potentially lead to aggravated near-ground pollution levels and increased risk of asthma and allergy82. Ground-level reflective pavements, an urban heat-mitigation strategy used for roads and parking lots in many cities, may create unintended glare and increase pedestrian heat stress when reflecting solar radiation83. Policies to improve thermal comfort by providing free winter heating with solid fuels may result in aggregated air pollution and cumulatively contribute to life-expectancy reduction84. Overlooking these unforeseen detrimental outcomes when implementing longevity-oriented strategies to mitigate and adapt to climate change may exert extra burdens on public health and can jeopardize the healthy aging of urban residents.

Longevity-ready cities reduce health disparities that emerge throughout life

Interventions focusing only on older populations in most age-friendly city initiatives are unlikely to resolve existing gaps in healthy longevity across different groups of people. These gaps often stem from interactions between ambient physical environments and socioeconomic determinants that accumulate over the life course85,86. Environmental exposures are one of the major causes of the substantial differences in life expectancy across socioeconomic status24. Research across countries worldwide has shown that lower socioeconomic status is associated with limited access to healthy outdoor environments, higher exposure to environmental toxins and stressors (Box 1), and greater health risks at all ages87,88,89. For instance, children of color in Detroit, Michigan, face a disproportionate burden of lead exposure that begins in utero, which is associated with impaired brain development and cognitive functioning90. Disparities in traffic safety and access to green spaces are observed in many cities; wealthier and less racially and ethnically diverse neighborhoods tend to have fewer traffic injuries and more accessible green spaces91,92,93,94. Similar evidence exists for the indoor environment; for example, poverty is associated with a lack of access to clean fuels95, exposing poor urban inhabitants to increasing risks of chronic diseases. Likewise, groups with low socioeconomic status in urban populations are more likely to experience differential economic losses, infrastructure disruptions, and health risks (injuries, illnesses, and deaths) from natural disasters and climate change75,96,97. Differences in life expectancies and healthy longevity around the globe will probably persist, or even be magnified, if these gaps are overlooked. The COVID-19 pandemic has exemplified how existing, deeply-seated disparities can be further exacerbated, disproportionately harming low-income countries, communities of low socioeconomic status, and people from racial or ethnic minority groups98,99.

Conceptually, gaps within populations at different ages can be expressed as discrepancies among individuals in their functional capacity (for example, respiratory capacity, brain functioning, muscle strength, and cardiovascular performance, all of which are closely related to life expectancy and healthy longevity; Box 1)4,100 (Fig. 3). In general, the functional capacity gradually increases after the prenatal period, reaches its maximum in early adulthood stage, and then gradually decreases with age and experiences more rapid losses at older age, although the rate of change can vary (that is, it is not necessarily monotonic) with the interactions of individuals with the ambient environment. Meanwhile, gaps among population subgroups may also increase and become more remarkably visible in later life5, mainly because the disproportional exposure to environmental risks generally accumulates over time. Sustainable development of cities and communities requires the physical environment to be designed to minimize and prevent health disparities among individuals and improve the aging trajectory (Box 1) of all urban residents. Such efforts can be schematically described as the arrows in Fig. 3, which bump up the dashed curves to curb further deterioration. Compared with most age-friendly city initiatives that focus on older populations (dashed arrows)8, longevity-ready cities implement interventions that reduce disparities at all life stages (solid arrows). Theoretically, the latter approach will therefore probably be more efficient, and will require less effort (Fig. 3), to achieve a more equitable and integrated society and to better prepare for century-long lives.

Fig. 3: The influence of disparities in the urban physical environment on functional capacity that evolves across the life course.
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The gray band represents the disability threshold for functional capacity. The solid gray curve represents the high functional capacity group, whereas the dashed curves in different colors represent groups with relatively lower functional capacity due to exposures at earlier life stages. Gaps between the solid curve and dashed ones are gaps in functional capacity induced by possible disparities that emerge at different life stages. Solid and dashed arrows represent gaps that would be eliminated by longevity-oriented urban planning and current age-friendly city initiatives, respectively, while the length of each arrow denotes the amount of effort needed. Adapted from ref. 100.

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Discussion and outlook

The concept of longevity-ready cities complements the age-friendly cities model by incorporating a life-course perspective, which emphasizes environmental influences that occur throughout life. Truly realizing longevity-ready cities demands a deeper understanding of environmental influences on aging and longevity. However, our current understanding of the ways in which urban physical environments cumulatively affect healthy longevity is mostly based on cross-sectional surveys or short-term longitudinal studies. More long-term prospective and retrospective cohort studies with controlled confounders are therefore imperative to disentangle the life-course impacts of urban physical environmental factors, especially those that have emerged in recent years (for example, smart home devices and autonomous vehicles). Similar studies that assess the long-term benefits and risks of existing policies and approaches are also important. Such cohort studies will substantially benefit implementation of future policies, given that the potential positive impacts of urban-planning policies on health may emerge slowly over the course of many years. One example is the widely implemented low-emission zones in many European cities (many have been in place since the late 2000s), which reduce air-pollution exposure. The long-term benefits of these zones were observed only recently101. Conclusions from these studies will also help quantify the tradeoffs between up-front costs of urban-planning interventions and the long-term benefits they bring to healthy longevity and prioritize the most cost-effective planning strategies when financial resources are limited.

With the focus of interventions on populations beyond older adults, many planning measures for longevity-ready cities are inherently similar to existing urban sustainable design strategies that improve general environmental quality (although with different objectives: healthy longevity versus general public health). This suggests that the proposed concept can be readily integrated into many ongoing efforts. Many initiatives for age-friendly cities that are aimed at improving the urban physical environment for older populations have encountered funding reductions and budget cuts6,102. With the potential of being incorporated into a wider array of existing policies and investments, longevity-ready cities could better utilize available resources and alleviate some financial predicament. Furthermore, the needs of cohort studies on life-course environmental impacts, as a vital component of longevity-ready cities, can potentially motivate collaborations with research institutions and attract funding from agencies beyond local and regional governments. Therefore, mainstreaming a life-course perspective in existing ordinances and holistic plans should foster and accelerate the transitions of urban environments to prepare for and cope with population aging in future cities.

One of the challenges of achieving equitable aging is the disparity in health outcomes among different subgroups of older populations. This has been recognized as a core indicator in the assessments of age-friendly cities103. Similarly, resolving health disparities is an essential part of longevity-ready cities. With a life-course consideration of disparities in environmental exposures, longevity-ready cities could more effectively tackle later-life inequities by reducing environmental disadvantages in early life stages104,105. In addition, health and longevity disparities in urban populations are determined by several interacting, dynamic factors, which include not only physical environments, but the long-term impacts of social environments (for example, family engagement and civic involvement)15 and the distribution of wealth and material resources106. Fundamentally resolving the health disparities in cities will require efforts toward addressing all these factors. Although we only focus on the urban physical environment herein, a life-course perspective of social domains in longevity-ready cities (Box 1) is equally important11, which can further improve the efficacy of social interventions and services.

The aging of urban populations can vary in different cities and countries and can dynamically change over time, as induced by regional and international migrations, economic developments, urban-regeneration projects and gentrification, and geographical, demographical, and cultural diversity5,8,107. This dynamic nature can become one of the major obstacles to the effectiveness and continuity of longevity-oriented policies and actions, which necessitates adaptive designs and frequent amendments. Knowledge transfers through communications and networks could help changing cities identify potential, evidence-based solutions. Similar to many age-friendly city initiatives4,8, the success of longevity-ready cities heavily relies on the concerted collaboration of multiple sectors, along with the engagement of policy makers, planners, designers, researchers, and beneficiaries of all ages. Integrating policies and research in longevity-oriented action plans will raise awareness of the determinants of healthy longevity among stakeholders (especially the private sector) while creating opportunities for partnerships. Moreover, the bottom-up participation of multiple generations in planning is critical, and this can stimulate their connections to one another and help reconcile potential conflicts by crafting actions that will fulfill different needs of different groups. Involving younger generations in the discussion to, for example, learn how they picture the cities they would like to live in when they grow old, could also benefit dynamic and adaptive policy making.

Conclusions

In an era of rapid global aging and urbanization, cities have unprecedented opportunities to mitigate and adapt to the unexpected challenges related to increased life expectancies and to positively support healthier, longer lives through intentional and well-informed planning. As century-long lives become the norm, it is imperative that we appreciate the cumulative effects of urban environments on healthy longevity, and design and reshape cities to optimize very long lives. Such a viewpoint calls for holistic considerations of how the urban physical environment may evolve in a changing climate and the pros and cons of various planning practices. In addition, life-course considerations of environmental exposures will minimize potential disparities in both life span and health span (Box 1), starting at the source. While the focus of this Perspective is on the urban physical environment, the concept of longevity-ready cities can be naturally extended to social determinants and municipal services and should permeate every phase of urban design and planning if possible.