Characterization of the Punta Toro species complex (genus Phlebovirus, family Bunyaviridae)

J Gen Virol. 2015 Aug;96(8):2079-2085. doi: 10.1099/vir.0.000170. Epub 2015 May 1.

Abstract

Punta Toro virus (PTV), a member of the PTV complex, is a relatively common causative agent of febrile illness in Panama that is often misdiagnosed as 'dengue' or 'influenza'. Currently, only two named members make up this species complex, PTV and Buenaventura virus (BUEV). Genomic and antigenic characterization of 17 members of the PTV complex, nine of which were isolated from human acute febrile illness cases, reveals that this species complex is composed of six distant viruses. We propose to add four additional new viruses, designated Leticia virus, Cocle virus, Campana virus and Capira virus.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Antibodies, Viral
  • Bunyaviridae Infections / immunology
  • Bunyaviridae Infections / virology*
  • Cross Reactions
  • Fever / immunology
  • Fever / virology*
  • Humans
  • Insect Vectors / virology
  • Molecular Sequence Data
  • Panama
  • Phlebovirus / classification
  • Phlebovirus / genetics
  • Phlebovirus / immunology
  • Phlebovirus / isolation & purification*
  • Phylogeny
  • Psychodidae / virology

Substances

  • Antibodies, Viral