Skip to main content

Diabetes Management in the United States

  • Chapter
  • First Online:
The Diabetes Textbook

Abstract

In 2020, diabetes affected 37.3 million Americans, of whom over 20% remained unaware of their diagnosis. Diabetes is one of the leading contributors of rising healthcare costs in the United States and disproportionately affects Americans from minority race/ethnicities and lower socioeconomic backgrounds, leading to disparities in diabetes care across the United States. Despite advances in care and established evidence-based recommendations for screening and management to prevent micro- and macrovascular complications of diabetes, control of diabetes-related risk factors (including glycemic, blood pressure, and lipid indices) has plateaued and more recently declined. With this, rates of emergency department use and complications have started to increase again since 2015, despite marked declines from 1990 to 2010. Promising advances in therapeutics, including SGLT2 inhibitors, GLP-1 receptor agonists, and DPP4 inhibitors, have the potential to improve glycemic control and cardio-metabolic outcomes for patients with diabetes, yet cost remains a barrier to access for most Americans. This chapter reviews US guidelines for diabetes detection, management, and maintenance and provides a review of disparities in diabetes care and outcomes. Further, this chapter catalogues examples of approaches and implementation strategies used in the United States to improve diabetes care and related disparities at the health system, payer, and policy level.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. National Diabetes Statistics Report. Atlanta, GA: Centers for Disease Control and Prevention; 2020.

    Google Scholar 

  2. Bullard KM, et al. Prevalence of diagnosed diabetes in adults by diabetes type - United States, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(12):359–61.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Gerstein HC, et al. Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies. Diabetes Res Clin Pract. 2007;78(3):305–12.

    Article  PubMed  Google Scholar 

  4. Menke A, et al. Prevalence of and trends in diabetes among adults in the United States, 1988-2012. JAMA. 2015;314(10):1021–9.

    Article  CAS  PubMed  Google Scholar 

  5. Dall TM, et al. The economic burden of elevated blood glucose levels in 2017: diagnosed and undiagnosed diabetes, gestational diabetes mellitus, and prediabetes. Diabetes Care. 2019;42(9):1661–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Centers for Disease Control and Prevention. National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014. U.S. Department of Health and Human Services 2014 [cited 2017 February]. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf.

  7. American Diabetes Association. Economic costs of diabetes in the U.S. in 2012. Diabetes Care. 2013;36(4):1033–46.

    Article  PubMed Central  Google Scholar 

  8. American Diabetes Association. Economic costs of diabetes in the U.S. in 2017. Diabetes Care. 2018;41(5):917–28.

    Article  PubMed Central  Google Scholar 

  9. Riddle MC, Herman WH. The cost of diabetes care-an elephant in the room. Diabetes Care. 2018;41(5):929–32.

    Article  PubMed  Google Scholar 

  10. Wills AK, et al. Maternal and paternal height and BMI and patterns of fetal growth: the Pune Maternal Nutrition Study. Early Hum Dev. 2010;86(9):535–40.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Lin SF, Lin JD, Huang YY. Diabetic ketoacidosis: comparisons of patient characteristics, clinical presentations and outcomes today and 20 years ago. Chang Gung Med J. 2005;28(1):24–30.

    CAS  PubMed  Google Scholar 

  12. Otto MH, et al. Diabetic ketoacidosis in Denmark: incidence and mortality estimated from public health registries. Diabetes Res Clin Pract. 2007;76(1):51–6.

    Article  Google Scholar 

  13. Chaturvedi N. The burden of diabetes and its complications: trends and implications for intervention. Diabetes Res Clin Pract. 2007;76(1):S3–12.

    Article  PubMed  Google Scholar 

  14. Zimmet P. Preventing diabetic complications: a primary care perspective. Diabetes Res Clin Pract. 2009;84(2):107–16.

    Article  PubMed  Google Scholar 

  15. Raheja BS, et al. DiabCare Asia—India Study: diabetes care in India—current status. J Assoc Physicians India. 2001;49:717–22.

    CAS  PubMed  Google Scholar 

  16. Danaei G, et al. Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. Lancet. 2006;368(9548):1651–9.

    Article  PubMed  Google Scholar 

  17. Aschner P. Diabetes trends in Latin America. Diabetes Metab Res Rev. 2002;18(Suppl 3):S27–31.

    Article  PubMed  Google Scholar 

  18. Stamler J, et al. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993;16(2):434–44.

    Article  CAS  PubMed  Google Scholar 

  19. Forbes JM, Cooper ME. Mechanisms of diabetic complications. Physiol Rev. 2013;93(1):137–88.

    Article  CAS  PubMed  Google Scholar 

  20. Wang L, et al. Trends in prevalence of diabetes and control of risk factors in diabetes among US adults, 1999-2018. JAMA. 2021;326(8):1–13.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Ali MK, et al. A cascade of care for diabetes in the United States: visualizing the gaps. Ann Intern Med. 2014;161(10):681–9.

    Article  PubMed  Google Scholar 

  22. Plantinga LC, et al. Prevalence of chronic kidney disease in US adults with undiagnosed diabetes or prediabetes. Clin J Am Soc Nephrol. 2010;5:673.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Ali MK, et al. Reach and use of Diabetes Prevention Services in the United States, 2016-2017. JAMA Netw Open. 2019;2(5):e193160.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Diabetes Prevention Program Research Group. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet. 2009;374(9702):1677–86.

    Article  PubMed Central  Google Scholar 

  25. Lindstrom J, et al. Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention tudy (DPS). Diabetologia. 2013;56(2):284–93.

    Article  CAS  PubMed  Google Scholar 

  26. Hoerger TJ, et al. Screening for type 2 diabetes mellitus: a cost-effectiveness analysis. Ann Intern Med. 2004;140(9):689–99.

    Article  PubMed  Google Scholar 

  27. Gillies CL, et al. Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis. BMJ. 2008;336(7654):1180–5.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Echouffo-Tcheugui JB, et al. Screening for type 2 diabetes and dysglycemia. Epidemiol Rev. 2011;33(1):63–87.

    Article  PubMed  Google Scholar 

  29. American Diabetes Association. Standards of medical care in diabetes-2021 abridged for primary care providers. Clin Diabetes. 2021;39(1):14–43.

    Article  PubMed Central  Google Scholar 

  30. US Preventive Services Task Force, et al. Screening for prediabetes and type 2 diabetes: US Preventive Services Task Force recommendation statement. JAMA. 2021;326(8):736–43.

    Article  Google Scholar 

  31. U.S. Preventive Services Task Force. Screening for type 2 diabetes mellitus in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2008;148(11):846–54.

    Article  Google Scholar 

  32. Bullard KM, et al. Receipt of glucose testing and performance of two US diabetes screening guidelines, 2007-2012. PLoS One. 2015;10(4):e0125249.

    Article  PubMed  PubMed Central  Google Scholar 

  33. O’Brien MJ, et al. Detecting dysglycemia using the 2015 United States Preventive Services Task Force screening criteria: a cohort analysis of community health center patients. PLoS Med. 2016;13(7):e1002074.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352(9131): 837–53.

    Google Scholar 

  35. Nathan DM, et al. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. N Engl J Med. 2005;353(25):2643–53.

    Article  PubMed  Google Scholar 

  36. Tandon N, Ali MK, Narayan KM. Pharmacologic prevention of microvascular and macrovascular complications in diabetes mellitus: implications of the results of recent clinical trials in type 2 diabetes. Am J Cardiovasc Drugs. 2012;12(1):7–22.

    Article  CAS  PubMed  Google Scholar 

  37. Chalmers J, Arima H. Management of hypertension: evidence from the blood pressure lowering treatment Trialists’ Collaboration and from major clinical trials. Pol Arch Med Wewn. 2009;119(6):373–80.

    PubMed  Google Scholar 

  38. Cholesterol Treatment Trialists’ (CTT) Collaboration. Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials. Lancet. 2015;385(9976):1397–405.

    Article  Google Scholar 

  39. Mohiuddin SM, et al. Intensive smoking cessation intervention reduces mortality in high-risk smokers with cardiovascular disease. Chest. 2007;131(2):446–52.

    Article  PubMed  Google Scholar 

  40. Fang M, et al. Trends in diabetes treatment and control in U.S. adults, 1999-2018. N Engl J Med. 2021;384(23):2219–28.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Ahmann AJ. Guidelines and performance measures for diabetes. Am J Manag Care. 2007;13(Suppl 2):S41–6.

    PubMed  Google Scholar 

  42. Pogach L, Aron DC. Sudden acceleration of diabetes quality measures. JAMA. 2011;305(7):709–10.

    Article  CAS  PubMed  Google Scholar 

  43. MN Community Measurement. 2012 health care quality report. 2012 [cited 2013 November]. http://mncm.org/wp-content/uploads/2013/04/2012_Final_HealthCareQualityReport_2.18.13.pdf.

  44. Inzucchi SE, et al. Management of hyperglycemia in type 2 diabetes, 2015: a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2015;38(1):140–9.

    Article  PubMed  Google Scholar 

  45. Ismail-Beigi F, et al. Individualizing glycemic targets in type 2 diabetes mellitus: implications of recent clinical trials. Ann Intern Med. 2011;154(8):554–9.

    Article  PubMed  Google Scholar 

  46. American Diabetes Association. Standards of medical care in diabetes—2014. Diabetes Care. 2014;37(Suppl 1):S14–80.

    Article  Google Scholar 

  47. International Diabetes Federation. IDF clinical practice guidelines. 2013 [cited 2014 March]. http://www.idf.org/guidelines.

  48. National Institute for Health and Care Excellence. Preventing type 2 diabetes—risk identification and interventions for individuals at high risk (PH38). Public Health Guidance 2013 [cited 2013 July 25]. http://www.nice.org.uk/guidance/index.jsp?action=byID&o=13791.

  49. Klein R, et al. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. IX. Four-year incidence and progression of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol. 1989;107(2):237–43.

    Article  CAS  PubMed  Google Scholar 

  50. Klein R, et al. The Wisconsin Epidemiologic Study of Diabetic retinopathy. X. Four-year incidence and progression of diabetic retinopathy when age at diagnosis is 30 years or more. Arch Ophthalmol. 1989;107(2):244–9.

    Article  CAS  PubMed  Google Scholar 

  51. Echouffo-Tcheugui JB, et al. Screening intervals for diabetic retinopathy and incidence of visual loss: a systematic review. Diabet Med. 2013;30(11):1272–92.

    Article  CAS  PubMed  Google Scholar 

  52. Photocoagulation treatment of proliferative diabetic retinopathy. Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS Report Number 8. The Diabetic Retinopathy Study Research Group. Ophthalmology. 1981;88(7):583–600.

    Google Scholar 

  53. Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group. Ophthalmology. 1991;98(5 Suppl):766–85.

    Google Scholar 

  54. Boulton AJ, et al. The global burden of diabetic foot disease. Lancet. 2005;366(9498):1719–24.

    Article  PubMed  Google Scholar 

  55. Boulton AJM. The diabetic foot: a global view. Diabetes Metab Res Rev. 2000;16(Suppl 1):S2–5.

    Article  PubMed  Google Scholar 

  56. Fernando DJ. The prevalence of neuropathic foot ulceration in Sri Lankan diabetic patients. Ceylon Med J. 1996;41(3):96–8.

    CAS  PubMed  Google Scholar 

  57. Björk S. The cost of diabetes and diabetes care. Diabetes Res Clin Pract. 2001;54(Suppl 1):13–8.

    Article  Google Scholar 

  58. Oyibo SO, et al. The effects of ulcer size and site, patient’s age, sex and type and duration of diabetes on the outcome of diabetic foot ulcers. Diabet Med. 2001;18(2):133–8.

    Article  CAS  PubMed  Google Scholar 

  59. Boulton AJM, et al. Comprehensive foot examination and risk assessment: a report of the task force of the Foot Care Interest Group of the American Diabetes Association, with endorsement by the American Association of Clinical Endocrinologists. Diabetes Care. 2008;31(8):1679–85.

    Article  PubMed  PubMed Central  Google Scholar 

  60. American Diabetes Association. 9. Microvascular complications and foot care. Diabetes Care. 2015;38(Suppl 1):S58–66.

    Article  Google Scholar 

  61. Colquhoun AJ, et al. Effectiveness of influenza vaccine in reducing hospital admissions in people with diabetes. Epidemiol Infect. 1997;119(3):335–41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  62. Heymann AD, et al. Reduced hospitalizations and death associated with influenza vaccination among patients with and without diabetes. Diabetes Care. 2004;27(11):2581–4.

    Article  PubMed  Google Scholar 

  63. Lau D, et al. Effectiveness of influenza vaccination in working-age adults with diabetes: a population-based cohort study. Thorax. 2013;68(7):658–63.

    Article  PubMed  Google Scholar 

  64. Pozzilli P, et al. The immune response to influenza vaccination in diabetic patients. Diabetologia. 1986;29(12):850–4.

    Article  CAS  PubMed  Google Scholar 

  65. Rodriguez-Blanco T, et al. Relationship between annual influenza vaccination and winter mortality in diabetic people over 65 years. Hum Vaccin Immunother. 2012;8(3):363–70.

    Article  PubMed  Google Scholar 

  66. Ali MK, et al. Cardiovascular and renal burdens of prediabetes in the USA: analysis of data from serial cross-sectional surveys, 1988-2014. Lancet Diabetes Endocrinol. 2018;6(5):392–403.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Gregg EW, et al. Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med. 2014;370(16):1514–23.

    Article  CAS  PubMed  Google Scholar 

  68. Gregg EW, et al. Trends in lifetime risk and years of life lost due to diabetes in the USA, 1985-2011: a modelling study. Lancet Diabetes Endocrinol. 2014;2(11):867–74.

    Article  PubMed  Google Scholar 

  69. Benoit SR, et al. Trends in emergency department visits and inpatient admissions for hyperglycemic crises in adults with diabetes in the U.S., 2006-2015. Diabetes Care. 2020;43(5):1057–64.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  70. Gregg EW, Hora I, Benoit SR. Resurgence in diabetes-related complications. JAMA. 2019;321(19):1867–8.

    Article  PubMed  Google Scholar 

  71. Centers for Disease Control and Prevention. National Diabetes Surveillance System. U.S. Department of Health and Human Services [cited 2017 February]. http://www.cdc.gov/diabetes/data/national.html.

  72. Bardenheier BH, et al. Disability-free life-years lost among adults aged >/=50 years with and without diabetes. Diabetes Care. 2016;39(7):1222–9.

    Article  PubMed  Google Scholar 

  73. Griffin S. Diabetes care in general practice: meta-analysis of randomised control trials. BMJ. 1998;317(7155):390–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  74. Atlas SJ, et al. Patient-physician connectedness and quality of primary care. Ann Intern Med. 2009;150(5):325–35.

    Article  PubMed  PubMed Central  Google Scholar 

  75. Morrison F, et al. Performance of primary care physicians and other providers on key process measures in the treatment of diabetes. Diabetes Care. 2013;36(5):1147–52.

    Article  PubMed  PubMed Central  Google Scholar 

  76. Saudek CD. The role of primary care professionals in managing diabetes. Clin Diabetes. 2002;20(2):65–6.

    Article  Google Scholar 

  77. Ashman J, Talwalkar A, Taylor S. Age differences in visits to office-based physicians by patients with diabetes: United States, 2010. In: NCHS data brief. Hyattsville, MD: National Center for Health Statistics; 2014.

    Google Scholar 

  78. OECD. Health at a glance; 2015.

    Google Scholar 

  79. Peters AL, et al. Quality of outpatient care provided to diabetic patients. A health maintenance organization experience. Diabetes Care. 1996;19(6):601–6.

    Article  CAS  PubMed  Google Scholar 

  80. Ali MK, et al. Achievement of goals in U.S. diabetes care, 1999-2010. N Engl J Med. 2013;368(17):1613–24.

    Article  CAS  PubMed  Google Scholar 

  81. Zgibor JC, Songer TJ. External barriers to diabetes care: addressing personal and health systems issues. Diabetes Spectr. 2001;14(1):23–8.

    Article  Google Scholar 

  82. Grintsova O, Maier W, Mielck A. Inequalities in health care among patients with type 2 diabetes by individual socio-economic status (SES) and regional deprivation: a systematic literature review. Int J Equity Health. 2014;13:43.

    Article  PubMed  PubMed Central  Google Scholar 

  83. Connolly V, et al. Diabetes prevalence and socioeconomic status: a population based study showing increased prevalence of type 2 diabetes mellitus in deprived areas. J Epidemiol Community Health. 2000;54(3):173–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  84. Zhang JX, et al. Insurance status and quality of diabetes care in community health centers. Am J Public Health. 2009;99(4):742–7.

    Article  PubMed  PubMed Central  Google Scholar 

  85. Zhang X, et al. Access to health care and control of ABCs of diabetes. Diabetes Care. 2012;35(7):1566–71.

    Article  PubMed  PubMed Central  Google Scholar 

  86. Stark Casagrande S, Cowie CC. Health insurance coverage among people with and without diabetes in the U.S. adult population. Diabetes Care. 2012;35(11):2243–9.

    Article  PubMed  PubMed Central  Google Scholar 

  87. Saaddine JB, et al. A diabetes report card for the United States: quality of care in the 1990s. Ann Intern Med. 2002;136(8):565–74.

    Article  PubMed  Google Scholar 

  88. Mercado CI, et al. Differences in U.S. rural-urban trends in diabetes ABCS, 1999-2018. Diabetes Care. 2021;44:1766.

    Article  CAS  PubMed  Google Scholar 

  89. Schmittdiel JA, et al. Why don’t diabetes patients achieve recommended risk factor targets? Poor adherence versus lack of treatment intensification. J Gen Intern Med. 2008;23(5):588–94.

    Article  PubMed  PubMed Central  Google Scholar 

  90. Schillinger D, et al. Association of health literacy with diabetes outcomes. JAMA. 2002;288(4):475–82.

    Article  PubMed  Google Scholar 

  91. Norris SL, et al. Self-management education for adults with type 2 diabetes: a meta-analysis of the effect on glycemic control. Diabetes Care. 2002;25(7):1159–71.

    Article  PubMed  Google Scholar 

  92. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487–97.

    Article  CAS  PubMed  Google Scholar 

  93. Karter AJ, et al. Barriers to insulin initiation: the translating research into action for diabetes insulin starts project. Diabetes Care. 2010;33(4):733–5.

    Article  PubMed  PubMed Central  Google Scholar 

  94. Ratanawongsa N, et al. Getting under the skin of clinical inertia in insulin initiation: the translating research into action for diabetes (TRIAD) insulin starts project. Diabetes Educ. 2012;38(1):94–100.

    Article  PubMed  PubMed Central  Google Scholar 

  95. The TRIAD Study Group. Health systems, patients factors, and quality of care for diabetes: a synthesis of findings from the TRIAD study. Diabetes Care. 2010;33(4):940–7.

    Article  PubMed Central  Google Scholar 

  96. Munshi MN, et al. Assessment of barriers to improve diabetes management in older adults: a randomized controlled study. Diabetes Care. 2013;36(3):543–9.

    Article  PubMed  PubMed Central  Google Scholar 

  97. Reed M, et al. Outpatient electronic health records and the clinical care and outcomes of patients with diabetes mellitus. Ann Intern Med. 2012;157(7):482–9.

    Article  PubMed  PubMed Central  Google Scholar 

  98. Karter AJ, et al. Out-of-pocket costs and diabetes preventive services: the translating research into action for diabetes (TRIAD) study. Diabetes Care. 2003;26(8):2294–9.

    Article  PubMed  Google Scholar 

  99. Geiss LS, et al. Increasing prevalence of diagnosed diabetes—United States and Puerto Rico, 1995–2010. Morb Mortal Wkly Rep. 2012;61(45):918–21.

    Google Scholar 

  100. Geiss LS, et al. Prevalence and incidence trends for diagnosed diabetes among adults aged 20 to 79 years, United States, 1980-2012. JAMA. 2014;312(12):1218–26.

    Article  CAS  PubMed  Google Scholar 

  101. Centers for Disease Control and Prevention. National diabetes statistics report: estimates of diabetes and its burden in the United States, 2014. U.S. Department of Health and Human Services; 2014. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf.

  102. Institute of Medicine, Brian DS, Adrienne YS, Alan RN. Unequal treatment: confronting racial and ethnic disparities in health Care. Washington, DC: The National Academies Press; 2003.

    Google Scholar 

  103. Sequist TD, et al. Physician performance and racial disparities in diabetes mellitus care. Arch Intern Med. 2008;168(11):1145–51.

    Article  CAS  PubMed  Google Scholar 

  104. Brown AF, et al. Race, ethnicity, socioeconomic position, and quality of care for adults with diabetes enrolled in managed care: the translating research into action for diabetes (TRIAD) study. Diabetes Care. 2005;28(12):2864–70.

    Article  PubMed  Google Scholar 

  105. Gregg EW, Williams DE, Geiss L. Changes in diabetes-related complications in the United States. N Engl J Med. 2014;371(3):286–7.

    CAS  PubMed  Google Scholar 

  106. Gaskin DJ, et al. Disparities in diabetes: the nexus of race, poverty, and place. Am J Public Health. 2014;104(11):2147–55.

    Article  PubMed  PubMed Central  Google Scholar 

  107. Bailey SC, et al. Update on health literacy and diabetes. Diabetes Educ. 2014;40(5):581–604.

    Article  PubMed  PubMed Central  Google Scholar 

  108. Institute of Medicine, Lynn N-B, Allison MP, David AK. Health literacy: a prescription to end confusion. Washington, DC: The National Academies Press; 2004.

    Google Scholar 

  109. Hogan DR, et al. Estimating the potential impact of insurance expansion on undiagnosed and uncontrolled chronic conditions. Health Aff. 2015;34(9):1554–62.

    Article  Google Scholar 

  110. Hu R, et al. Insurance, racial/ethnic, SES-related disparities in quality of care among US adults with diabetes. J Immigr Minor Health. 2014;16(4):565–75.

    Article  PubMed  Google Scholar 

  111. Sequist TD, et al. Primary-care clinician perceptions of racial disparities in diabetes care. J Gen Intern Med. 2008;23(5):678–84.

    Article  PubMed  PubMed Central  Google Scholar 

  112. White RO, Beech BM, Miller S. Health care disparities and diabetes care: practical considerations for primary care providers. Clin Diabetes. 2009;27(3):105–12.

    Article  PubMed  Google Scholar 

  113. Davidson JA. The increasing role of primary care physicians in caring for patients with type 2 diabetes mellitus. Mayo Clin Proc. 2010;85(12 Suppl):S3–4.

    Article  PubMed  PubMed Central  Google Scholar 

  114. Vigersky RA, et al. The clinical endocrinology workforce: current status and future projections of supply and demand. J Clin Endocrinol Metab. 2014;99(9):3112–21.

    Article  CAS  PubMed  Google Scholar 

  115. Leinung MC, et al. Comparison of diabetes care provided by an endocrinology clinic and a primary-care clinic. Endocr Pract. 2000;6(5):361–6.

    Article  CAS  PubMed  Google Scholar 

  116. American Diabetes Association. 10. Cardiovascular disease and risk management: standards of medical care in diabetes—2021. Diabetes Care. 2021;44(Suppl 1):S125–50.

    Article  Google Scholar 

  117. American Diabetes Association. 11. Microvascular complications and foot care: standards of medical care in diabetes—2021. Diabetes Care. 2021;44(Suppl 1):S151–67.

    Article  Google Scholar 

  118. American Diabetes Association. 9. Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes—2021. Diabetes Care. 2021;44(Suppl 1):S111–24.

    Article  Google Scholar 

  119. Zinman B, Lachin JM, Inzucchi SE. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2016;374(11):1094.

    PubMed  Google Scholar 

  120. Perkovic V, et al. Canagliflozin and renal outcomes in type 2 diabetes: results from the CANVAS program randomised clinical trials. Lancet Diabetes Endocrinol. 2018;6(9):691–704.

    Article  CAS  PubMed  Google Scholar 

  121. Perkovic V, et al. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. N Engl J Med. 2019;380(24):2295–306.

    Article  CAS  PubMed  Google Scholar 

  122. Wiviott SD, et al. Dapagliflozin and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2019;380(4):347–57.

    Article  CAS  PubMed  Google Scholar 

  123. Kristensen SL, et al. Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes Endocrinol. 2019;7(10):776–85.

    Article  CAS  PubMed  Google Scholar 

  124. Cornel JH, et al. Effect of sitagliptin on kidney function and respective cardiovascular outcomes in type 2 diabetes: outcomes from TECOS. Diabetes Care. 2016;39(12):2304–10.

    Article  CAS  PubMed  Google Scholar 

  125. Scirica BM, et al. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med. 2013;369(14):1317–26.

    Article  CAS  PubMed  Google Scholar 

  126. Marso SP, et al. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med. 2016;375(4):311–22.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  127. Marso SP, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375(19):1834–44.

    Article  CAS  PubMed  Google Scholar 

  128. Frias JP, et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med. 2021;385(6):503–15.

    Article  CAS  PubMed  Google Scholar 

  129. Gerstein HC, et al. Cardiovascular and renal outcomes with efpeglenatide in type 2 diabetes. N Engl J Med. 2021;385:896.

    Article  CAS  PubMed  Google Scholar 

  130. American Diabetes Association. 7. Diabetes technology: standards of medical care in diabetes—2021. Diabetes Care. 2021;44(Suppl 1):S85–99.

    Article  Google Scholar 

  131. Hua X, et al. Expenditures and prices of antihyperglycemic medications in the United States: 2002-2013. JAMA. 2016;315(13):1400–2.

    Article  PubMed  PubMed Central  Google Scholar 

  132. Cefalu WT, et al. Insulin access and affordability working group: conclusions and recommendations. Diabetes Care. 2018;41(6):1299–311.

    Article  PubMed  Google Scholar 

  133. Brown JB, Nichols GA, Perry A. The burden of treatment failure in type 2 diabetes. Diabetes Care. 2004;27(7):1535–40.

    Article  PubMed  Google Scholar 

  134. Renders CM, et al. Interventions to improve the management of diabetes in primary care, outpatient, and community settings: a systematic review. Diabetes Care. 2001;24(10):1821–33.

    Article  CAS  PubMed  Google Scholar 

  135. Tricco AC, et al. Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis. Lancet. 2012;379(9833):2252–61.

    Article  PubMed  Google Scholar 

  136. Griffin SJ, et al. Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial. Lancet. 2011;378(9786):156–67.

    Article  PubMed  PubMed Central  Google Scholar 

  137. Wagner EH, Austin BT, Von Korff M. Organizing care for patients with chronic illness. Milbank Q. 1996;74(4):511–44.

    Article  CAS  PubMed  Google Scholar 

  138. Gaede P, et al. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med. 2003;348(5):383–93.

    Article  PubMed  Google Scholar 

  139. Institute of Medicine Committee on Quality of Health Care in America. Crossing the quality chasm: a new health system for the 21st century. Washington, DC: National Academy Press; 2001.

    Google Scholar 

  140. O’Connor PJ, et al. Variation in quality of diabetes care at the levels of patient, physician, and clinic. Prev Chronic Dis. 2008;5(1):A15.

    PubMed  Google Scholar 

  141. Schmittdiel JA, et al. The effectiveness of diabetes care management in managed care. Am J Manag Care. 2009;15(5):295–301.

    PubMed  Google Scholar 

  142. McMahon GT, Dluhy RG. Diabetes report card--time for a winning streak. N Engl J Med. 2013;368(17):1650–1.

    Article  CAS  PubMed  Google Scholar 

  143. Stellefson M, Dipnarine K, Stopka C. The chronic care model and diabetes management in US primary care settings: a systematic review. Prev Chronic Dis. 2013;10:E26.

    Article  PubMed  PubMed Central  Google Scholar 

  144. Ali MK, et al. Effectiveness of a multicomponent quality improvement strategy to improve achievement of diabetes care goals: a randomized, controlled trial. Ann Intern Med. 2016;165(6):399–408.

    Article  PubMed  PubMed Central  Google Scholar 

  145. Raney LE. Integrating primary care and behavioral health: the role of the psychiatrist in the collaborative care model. Am J Psychiatry. 2015;172(8):721–8.

    Article  PubMed  Google Scholar 

  146. Katon WJ, et al. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363(27):2611–20.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  147. Rossom RC, et al. Impact of a national collaborative care initiative for patients with depression and diabetes or cardiovascular disease. Gen Hosp Psychiatry. 2017;44:77–85.

    Article  PubMed  Google Scholar 

  148. Lustman PJ, et al. Fluoxetine for depression in diabetes: a randomized double-blind placebo-controlled trial. Diabetes Care. 2000;23(5):618–23.

    Article  CAS  PubMed  Google Scholar 

  149. Lustman PJ, et al. Effects of nortriptyline on depression and glycemic control in diabetes: results of a double-blind, placebo-controlled trial. Psychosom Med. 1997;59(3):241–50.

    Article  CAS  PubMed  Google Scholar 

  150. Lustman PJ, et al. Cognitive behavior therapy for depression in type 2 diabetes mellitus. A randomized, controlled trial. Ann Intern Med. 1998;129(8):613–21.

    Article  CAS  PubMed  Google Scholar 

  151. Katon WJ, et al. The pathways study: a randomized trial of collaborative care in patients with diabetes and depression. Arch Gen Psychiatry. 2004;61(10):1042–9.

    Article  PubMed  Google Scholar 

  152. Ali MK, et al. Effect of a collaborative care model on depressive symptoms and glycated hemoglobin, blood pressure, and serum cholesterol among patients with depression and Diabetes in India: the INDEPENDENT Randomized Clinical Trial. JAMA. 2020;324(7):651–62.

    Article  CAS  PubMed  Google Scholar 

  153. Simon GE, et al. Cost-effectiveness of systematic depression treatment among people with diabetes mellitus. Arch Gen Psychiatry. 2007;64(1):65–72.

    Article  PubMed  Google Scholar 

  154. Blumenthal JA, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159(19):2349–56.

    Article  CAS  PubMed  Google Scholar 

  155. Testa MA, Simonson DC. Health economic benefits and quality of life during improved glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled, double-blind trial. JAMA. 1998;280(17):1490–6.

    Article  CAS  PubMed  Google Scholar 

  156. Wing RR, Phelan S, Tate D. The role of adherence in mediating the relationship between depression and health outcomes. J Psychosom Res. 2002;53(4):877–81.

    Article  PubMed  Google Scholar 

  157. Hennink MM, et al. How are qualitative methods used in diabetes research? A 30-year systematic review. Glob Public Health. 2017;12(2):200–19.

    Article  PubMed  Google Scholar 

  158. Simon GE, et al. Cost-effectiveness of systematic depression treatment for high utilizers of general medical care. Arch Gen Psychiatry. 2001;58(2):181–7.

    Article  CAS  PubMed  Google Scholar 

  159. Kates N, Craven M. Shared mental health care. Update from the Collaborative Working Group of the College of Family Physicians of Canada and the Canadian Psychiatric Association. Can Fam Physician. 2002;48:936.

    PubMed  PubMed Central  Google Scholar 

  160. Meadows GN. Establishing a collaborative service model for primary mental health care. Med J Aust. 1998;168(4):162–5.

    Article  CAS  PubMed  Google Scholar 

  161. Wagner EH. Chronic disease management: what will it take to improve care for chronic illness? Eff Clin Pract. 1998;1(1):2–4.

    CAS  PubMed  Google Scholar 

  162. Von Korff M, et al. Collaborative management of chronic illness. Ann Intern Med. 1997;127(12):1097–102.

    Article  Google Scholar 

  163. Kilo CM, Wasson JH. Practice redesign and the patient-centered medical home: history, promises, and challenges. Health Aff (Millwood). 2010;29(5):773–8.

    Article  PubMed  Google Scholar 

  164. Bojadzievski T, Gabbay RA. Patient-centered medical home and diabetes. Diabetes Care. 2011;34(4):1047–53.

    Article  PubMed  PubMed Central  Google Scholar 

  165. Health Affairs. Patient-centered medical homes. Health policy Briefs 2010 [cited 2017 August 3]. http://www.healthaffairs.org/healthpolicybriefs/brief.php?brief_id=25.

  166. American Academy of Family Physicians (AAFP), American Academy of Pediatrics (AAP), American College of Physicians (ACP), American Osteopathic Association (AOA). Joint principles of the patient-centered medical home. 2007 [cited 2017 August 3]. http://www.aafp.org/dam/AAFP/documents/practice_management/pcmh/initiatives/PCMHJoint.pdf.

  167. Wagner EH, Austin BT, Von Korff M. Improving outcomes in chronic illness. Manag Care Q. 1996;4(2):12–25.

    CAS  PubMed  Google Scholar 

  168. Khan L, Mincemoyer S, Gabbay RA. Diabetes registries: where we are and where are we headed? Diabetes Technol Ther. 2009;11(4):255–62.

    Article  PubMed  Google Scholar 

  169. Rittenhouse DR, et al. Measuring the medical home infrastructure in large medical groups. Health Aff (Millwood). 2008;27(5):1246–58.

    Article  PubMed  Google Scholar 

  170. US Department of Veterans Affairs. Patient Aligned Care Team (PACT). 2017 [cited 2017 August 3]. https://www.patientcare.va.gov/primarycare/PACT.asp.

  171. Kerr EA, et al. Diabetes care quality in the veterans affairs health care system and commercial managed care: the TRIAD study. Ann Intern Med. 2004;141(4):272–81.

    Article  PubMed  Google Scholar 

  172. National Committee for Quality Assurance (NCQA). Patient-Centered Medical Home (PCMH) Recognition. 2017 [cited 2017 August 3]. http://www.ncqa.org/Programs/Recognition/Practices/PatientCenteredMedicalHomePCMH.aspx.

  173. National Committee for Quality Assurance (NCQA). Latest evidence: benefits of the patient-centered medical home. 2017 [cited 2017 August 3]. http://www.ncqa.org/programs/recognition/practices/pcmh-evidence#_ftn1.

  174. Jackson GL, et al. Improving patient care. The patient centered medical home. A systematic review. Ann Intern Med. 2013;158(3):169–78.

    Article  PubMed  Google Scholar 

  175. Gabbay RA, et al. Multipayer patient-centered medical home implementation guided by the chronic care model. Jt Comm J Qual Patient Saf. 2011;37(6):265–73.

    PubMed  Google Scholar 

  176. Friedberg MW, et al. Association between participation in a multipayer medical home intervention and changes in quality, utilization, and costs of care. JAMA. 2014;311(8):815–25.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  177. Solberg LI, et al. Differences in diabetes care with and without certification as a medical home. Ann Fam Med. 2020;18(1):66–72.

    Article  PubMed  PubMed Central  Google Scholar 

  178. Carrier E, Gourevitch MN, Shah NR. Medical homes: challenges in translating theory into practice. Med Care. 2009;47(7):714–22.

    Article  PubMed  PubMed Central  Google Scholar 

  179. American College of Physicians. Center for practice improvement & innovation’s (CPII) two year study of 34 PCMHs. 2008 [cited 2017 August 3]. https://www.acponline.org/practice-resources/business-resources/payment/models/pcmh/resources/articles-reports-and-abstracts.

  180. National Committee for Quality Assurance (NCQA). HEDIS® & performance measurement. [cited 2017 August 3]. http://www.ncqa.org/hedis-quality-measurement.

  181. National Diabetes Quality Improvement Alliance. Performance measurement set for adult diabetes, NIDDKD (National Institute of Diabetes and Digestive and Kidney Diseases), Chicago, IL; 2005.

    Google Scholar 

  182. Centers for Medicare and Medicaid Services. Medicare managed care manual. Chapter 11 - Medicare advantage application procedures and contract requirements [cited 2017 August 3]. https://www.cms.gov/Regulations-and-Guidance/Guidance/Manuals/downloads/mc86c11.pdf.

  183. US Department of Health and Human Services. Payment for medicare advantage plans: policy issues and options. Office of the Assistant Secretary for Planning and Evaluation [cited 2017 August 3]. https://aspe.hhs.gov/basic-report/payment-medicare-advantage-plans-policy-issues-and-options.

  184. Health affairs. Pay-for-performance. Health Policy Briefs 2012 [cited 2017 August 3]. http://www.healthaffairs.org/healthpolicybriefs/brief.php?brief_id=78.

  185. Rosenthal MB, Frank RG. What is the empirical basis for paying for quality in health care? Med Care Res Rev. 2006;63(2):135–57.

    Article  PubMed  Google Scholar 

  186. Petersen LA, et al. Does pay-for-performance improve the quality of health care? Ann Intern Med. 2006;145(4):265–72.

    Article  PubMed  Google Scholar 

  187. Werner RM, et al. The effect of pay-for-performance in hospitals: lessons for quality improvement. Health Aff. 2011;30(4):690–8.

    Article  Google Scholar 

  188. Damberg CL, et al. Measuring success in health care value-based purchasing programs. RAND Health Q. 2014;4(3):9. http://www.rand.org/content/dam/rand/pubs/research_reports/RR300/RR306/RAND_RR306.pdf.

    PubMed  PubMed Central  Google Scholar 

  189. Institute of Medicine, Board on Health Care Services, Committee on Redesigning Health Insurance Performance Measures, Payment, and Performance Improvement Programs. Rewarding provider performance: aligning incentives in medicare. Washington, DC: The National Academies Press; 2006.

    Google Scholar 

  190. Casalino LP, et al. Will pay-for-performance and quality reporting affect health care disparities? Health Aff (Millwood). 2007;26(3):w405–14.

    Article  PubMed  Google Scholar 

  191. Doran T, et al. Pay-for-performance programs in family practices in the United Kingdom. N Engl J Med. 2006;355(4):375–84.

    Article  CAS  PubMed  Google Scholar 

  192. Eijkenaar F. Key issues in the design of pay for performance programs. Eur J Health Econ. 2013;14(1):117–31.

    Article  PubMed  Google Scholar 

  193. McDonald R, Roland M. Pay for performance in primary care in England and California: comparison of unintended consequences. Ann Fam Med. 2009;7(2):121–7.

    Article  PubMed  PubMed Central  Google Scholar 

  194. Thorpe KE. Analysis & commentary: the affordable care act lays the groundwork for a national diabetes prevention and treatment strategy. Health Aff (Millwood). 2012;31(1):61–6.

    Article  PubMed  Google Scholar 

  195. Myerson R, Laiteerapong N. The affordable care act and diabetes diagnosis and care: exploring the potential impacts. Curr Diab Rep. 2016;16(4):27.

    Article  PubMed  PubMed Central  Google Scholar 

  196. Ludwig L, et al. The impact of COVID-19 lockdown on metabolic control and access to healthcare in people with Diabetes: the CONFI-DIAB cross-sectional study. Diabetes Ther. 2021;12(8):2207–21.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  197. NEW DATA ALERT: COVID-19 brings crisis of access for millions living with diabetes, August 16, 2021. https://www.diabetes.org/newsroom/press-releases/COVID-19-brings-crisis-of-access-for-millions-living-with-diabetes.

  198. Narayan KM, et al. Diabetes translation research: where are we and where do we want to be? Ann Intern Med. 2004;140(11):958–63.

    Article  PubMed  Google Scholar 

  199. Narayan KM, et al. Translation research for chronic disease: the case of diabetes. Diabetes Care. 2000;23(12):1794–8.

    Article  CAS  PubMed  Google Scholar 

  200. Garfield SA, et al. Considerations for diabetes translational research in real-world settings. Diabetes Care. 2003;26(9):2670–4.

    Article  PubMed  Google Scholar 

  201. Haw JS, Narayan KM, Ali MK. Quality improvement in diabetes-successful in achieving better care with hopes for prevention. Ann N Y Acad Sci. 2015;1353(1):138–51.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohammed K. Ali .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Shah, M.K., Khan, F.N., Ali, M.K. (2023). Diabetes Management in the United States. In: Rodriguez-Saldana, J. (eds) The Diabetes Textbook. Springer, Cham. https://doi.org/10.1007/978-3-031-25519-9_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-25519-9_19

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-25518-2

  • Online ISBN: 978-3-031-25519-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics