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Diabetes Management in Asia

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Abstract

In the first edition of the book chapter on “Diabetes Management in Asia,” we first presented the available evidence on the diabetes burdens by urban and rural settings including young-onset diabetes and economic impact in Asia. Second, we described the status of diabetes management in Asia in terms of screening and diagnosis of diabetes and treatment for diabetes complications and comorbidities. Third, challenges for diabetes management in Asia from the perspective of health systems, provider, and patients were reported alongside the use of complementary and alternative medicines. Lastly, we synthesized the evidence around models for diabetes prevention and care in Asia.

In this update of the previous book chapter, our goal is to provide the most recent available evidence around the diabetes burdens, care cascade, challenges, and newer approaches to prevention and care in Asia, with particular emphasis on the special forms of diabetes in Asia, quality improvement initiatives in outpatient settings, and policies and incentives to address and sustain quality in diabetes care. Also, we highlight the impact of COVID-19 pandemic on people with diabetes in Asia and the role of telemedicine and digital health strategies to build resilient health systems in order to overcome some of the challenges of regular monitoring and care during future pandemics in Asia region.

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References

  1. Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018;14(2):88–98.

    Article  PubMed  Google Scholar 

  2. Pradeepa R, Mohan V. Prevalence of type 2 diabetes and its complications in India and economic costs to the nation. Eur J Clin Nutr. 2017;71(7):816–24.

    Article  CAS  PubMed  Google Scholar 

  3. Magliano DJ, Sacre JW, Harding JL, Gregg EW, Zimmet PZ, Shaw JE. Young-onset type 2 diabetes mellitus—implications for morbidity and mortality. Nat Rev Endocrinol. 2020;16(6):321–31.

    Article  PubMed  Google Scholar 

  4. Home, resources, diabetes L with, Acknowledgement, FAQs, Contact, et al. IDF Diabetes Atlas | Tenth Edition [Internet]. [cited 2022 Apr 8]. https://diabetesatlas.org/.

  5. Saeedi P, Salpea P, Karuranga S, Petersohn I, Malanda B, Gregg EW, et al. Mortality attributable to diabetes in 20-79 years old adults, 2019 estimates: results from the International Diabetes Federation Diabetes Atlas, 9th edition. Diabetes Res Clin Pract. 2020;162:108086.

    Article  PubMed  Google Scholar 

  6. Lin X, Xu Y, Pan X, Xu J, Ding Y, Sun X, et al. Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025. Sci Rep. 2020;10(1):14790.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Ramachandran A, Snehalatha C, Shetty AS, Nanditha A. Trends in prevalence of diabetes in Asian countries. World J Diabetes. 2012;3(6):110–7.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Mobasseri M, Shirmohammadi M, Amiri T, Vahed N, Hosseini Fard H, Ghojazadeh M. Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis. Health Promot Perspect. 2020;10(2):98–115.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Nanditha A, Snehalatha C, Satheesh K, Susairaj P, Simon M, Vijaya L, et al. Secular TRends in DiabEtes in India (STRiDE–I): change in prevalence in 10 years among urban and rural populations in Tamil Nadu. Diabetes Care. 2019;42(3):476–85.

    Article  PubMed  Google Scholar 

  10. Geldsetzer P, Manne-Goehler J, Theilmann M, Davies JI, Awasthi A, Vollmer S, et al. Diabetes and hypertension in India: a nationally representative study of 1.3 million adults. JAMA Intern Med. 2018;178(3):363–72.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Mao W, Yip C-MW, Chen W. Complications of diabetes in China: health system and economic implications. BMC Public Health. 2019;19(1):269.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Arambewela MH, Somasundaram NP, Jayasekara HBPR, Kumbukage MP, Jayasena PMS, Chandrasekara CMPH, et al. Prevalence of chronic complications, their risk factors, and the cardiovascular risk factors among patients with type 2 diabetes attending the diabetic clinic at a Tertiary Care Hospital in Sri Lanka. J Diabetes Res. 2018;2018:e4504287.

    Article  Google Scholar 

  13. Nguyen KT, Diep BTT, Nguyen VDK, Van Lam H, Tran KQ, Tran NQ. A cross-sectional study to evaluate diabetes management, control and complications in 1631 patients with type 2 diabetes mellitus in Vietnam (DiabCare Asia). Int J Diabetes Dev Ctries. 2020;40(1):70–9.

    Article  CAS  Google Scholar 

  14. Cholil AR, Lindarto D, Pemayun TGD, Wisnu W, Kumala P, Puteri HHS. DiabCare Asia 2012: diabetes management, control, and complications in patients with type 2 diabetes in Indonesia. Med J Indonesia. 2019;28(1):47–56.

    Article  Google Scholar 

  15. Chappidi M, Shivananjiah S, Thirthahalli C, Kunnavil R, Murthy NS. Complications of diabetes mellitus among patients attending the out-patient department of a tertiary care hospital. Int J Commun Med Public Health. 2017;5(1):341–8.

    Article  Google Scholar 

  16. Clinical profile and incidence of microvascular complications of childhood and adolescent onset type 1 and type 2 diabetes seen at a tertiary diabetes center in India. [cited 2021 Aug 12]. https://onlinelibrary.wiley.com/doi/10.1111/pedi.13033

  17. Singh K, Narayan KMV, Eggleston K. Economic impact of diabetes in South Asia: the magnitude of the problem. Curr Diab Rep. 2019;19(6):34.

    Article  PubMed  Google Scholar 

  18. Williams J, Allen L, Wickramasinghe K, Mikkelsen B, Roberts N, Townsend N. A systematic review of associations between non-communicable diseases and socioeconomic status within low- and lower-middle-income countries. J Glob Health. 2018;8(2):020409.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Oberoi S, Kansra P. Economic menace of diabetes in India: a systematic review. Int J Diabetes Dev Ctries. 2020;40(4):464–75.

    Article  PubMed  Google Scholar 

  20. Yang YS, Kwak SH, Park KS. Update on monogenic diabetes in Korea. Diabetes Metab J. 2020;44(5):627–39.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Park SS, Jang SS, Ahn CH, Kim JH, Jung HS, Cho YM, et al. Identifying pathogenic variants of monogenic diabetes using targeted panel sequencing in an East Asian Population. J Clin Endocrinol Metab. 2019;jc.2018-02397.

    Google Scholar 

  22. Nkonge KM, Nkonge DK, Nkonge TN. The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY). Clin Diabetes Endocrinol. 2020;6(1):20.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Riddle MC, Philipson LH, Rich SS, Carlsson A, Franks PW, Greeley SAW, et al. Monogenic diabetes: from genetic insights to population-based precision in care. Reflections from a Diabetes Care Editors’ Expert Forum. Diabetes Care. 2020;43(12):3117–28.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Misra S, Owen KR. Genetics of Monogenic diabetes: present clinical challenges. Curr Diab Rep. 2018;18(12):141.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Singh. Fibrocalculous pancreatic diabetes in a young female: a case report from South Gujarat [Internet]. [cited 2022 Apr 8]. https://www.journalofdiabetology.org/article.asp?issn=2078-7685;year=2019;volume=10;issue=3;spage=140;epage=142;aulast=Singh.

  26. Xia F, Zhou W, Wang B, Hu Y. Non-tropical fibrocalculous pancreatic diabetes: case reports and review of recent literature. J Int Med Res. 2020;48(7):300060520938967.

    Article  PubMed  Google Scholar 

  27. Patel HS, Jain SK. Study of prevalence and clinical presentation of fibrocalculous pancreatic diabetes in and around Jabalpur (Madhya Pradesh), Central India. Int J Med Sci Public Health. 2016;5(10):2168–72.

    Article  Google Scholar 

  28. Jiang P, Babazono A, Fujita T. Health inequalities among elderly type 2 diabetes mellitus patients in Japan. Popul Health Manag. 2020;23(3):264–70.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Aizawa T. Inequality in the treatment of diabetes and hypertension across residency status in China. Ethn Health. 2021;26(4):512–29.

    Article  PubMed  Google Scholar 

  30. Wang Z, Li X, Chen M. Socioeconomic factors and inequality in the prevalence and treatment of diabetes among middle-aged and elderly adults in China. J Diabetes Res. 2018;2018:1471808.

    Article  PubMed  PubMed Central  Google Scholar 

  31. The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 680 102 adults. The Lancet Healthy Longevity [Internet]. [cited 2022 Apr 10]. https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(21)00089-1/fulltext.

  32. Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. The Lancet [Internet]. [cited 2022 Apr 10]. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30994-2/fulltext.

  33. Manne-Goehler J, Geldsetzer P, Agoudavi K, Andall-Brereton G, Aryal KK, Bicaba BW, et al. Health system performance for people with diabetes in 28 low- and middle-income countries: a cross-sectional study of nationally representative surveys. PLoS Med. 2019;16(3):e1002751.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Huntriss R, Campbell M, Bedwell C. The interpretation and effect of a low-carbohydrate diet in the management of type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials. Eur J Clin Nutr. 2018;72(3):311–25.

    Article  CAS  PubMed  Google Scholar 

  35. Uma R, Bhavadharini B, Ranjani H, Mahalakshmi MM, Anjana RM, Unnikrishnan R, et al. Pregnancy outcome of gestational diabetes mellitus using a structured model of care: WINGS project (WINGS-10). J Obstet Gynaecol Res. 2017;43(3):468–75.

    Article  CAS  PubMed  Google Scholar 

  36. Jadhav RA, Hazari A, Monterio A, Kumar S, Maiya AG. Effect of physical activity intervention in prediabetes: a systematic review with meta-analysis. J Phys Act Health. 2017;14(9):745–55.

    Article  PubMed  Google Scholar 

  37. ICMR_GuidelinesType2diabetes2018_0.pdf [Internet]. [cited 2021 May 24]. https://main.icmr.nic.in/sites/default/files/guidelines/ICMR_GuidelinesType2diabetes2018_0.pdf.

  38. Gan S, Dawed AY, Donnelly LA, Nair ATN, Palmer CNA, Mohan V, et al. Efficacy of modern diabetes treatments DPP-4i, SGLT-2i, and GLP-1RA in White and Asian patients with diabetes: a systematic review and meta-analysis of randomized controlled trials. Diabetes Care. 2020;43(8):1948–57.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Gu T, Hong T, Zhang P, Tang S, Bi Y, Lu H, et al. Insulin glargine combined with oral antidiabetic drugs for Asians with type 2 diabetes mellitus: a pooled analysis to identify predictors of dose and treatment response. Diabetes Ther. 2018;9(2):771–87.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  40. Lu J-M. The role of glucagon-like peptide-1 receptor agonists in type 2 diabetes in Asia. Adv Ther. 2019;36(4):798–805.

    Article  CAS  PubMed  Google Scholar 

  41. Unnikrishnan R, Shah VN, Mohan V. Challenges in diagnosis and management of diabetes in the young. Clin Diabetes Endocrinol. 2016;2(1):18.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, et al. Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial. Lancet Diabetes Endocrinol. 2017;5(12):951–64. https://pubmed.ncbi.nlm.nih.gov/29079252/.

    Article  PubMed  Google Scholar 

  43. Ali MK, Chwastiak L, Poongothai S, Emmert-Fees KMF, Patel SA, Anjana RM, et al. Effect of a collaborative care model on depressive symptoms and glycated hemoglobin, blood pressure, and serum cholesterol among patients with depression and diabetes in India: the INDEPENDENT randomized clinical trial. JAMA. 2020;324(7):651–62.

    Article  CAS  PubMed  Google Scholar 

  44. Islek D, Weber MB, Ranjit Mohan A, Mohan V, Staimez LR, Harish R, et al. Cost-effectiveness of a stepwise approach vs standard care for diabetes prevention in India. JAMA Network Open. 2020;3(7):e207539.

    Article  PubMed  Google Scholar 

  45. WHO Coronavirus Disease (COVID-19) Dashboard. Bangladesh Physiotherapy Journal [Internet]. 2020 Sep 1 [cited 2022 Apr 10]. https://www.scienceopen.com/document?vid=2dda2c28-4a81-47cf-8383-6a9f5546c6c0.

  46. Trends in COVID-19-related in-hospital mortality: lessons learned from nationwide samples - PubMed [Internet]. [cited 2022 Apr 10]. https://pubmed.ncbi.nlm.nih.gov/33600776/.

  47. Laxminarayan R, Wahl B, Dudala SR, Gopal K, Mohan BC, Neelima S, et al. Epidemiology and transmission dynamics of COVID-19 in two Indian states. Science. 2020;370(6517):691–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  48. Mansfield KE, Mathur R, Tazare J, Henderson AD, Mulick AR, Carreira H, et al. Indirect acute effects of the COVID-19 pandemic on physical and mental health in the UK: a population-based study. Lancet Digit Health. 2021;3(4):e217–30.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Wang Z, Duan Y, Jin Y, Zheng Z-J. Coronavirus disease 2019 (COVID-19) pandemic: how countries should build more resilient health systems for preparedness and response. Glob Health J. 2020;4(4):139–45.

    Article  PubMed  PubMed Central  Google Scholar 

  50. Prabhakaran D, Jha D, Prieto-Merino D, Roy A, Singh K, Ajay VS, et al. Effectiveness of an mHealth-Based Electronic Decision Support System for Integrated Management of Chronic Conditions in Primary Care: The mWellcare Cluster-Randomized Controlled Trial. Circulation. 2019;139(3):380–91.

    Article  PubMed  Google Scholar 

Further Reading

  • Ali MK, Chwastiak L, Poongothai S, Emmert-Fees KMF, Patel SA, Anjana RM, et al. Effect of a collaborative care model on depressive symptoms and glycated hemoglobin, blood pressure, and serum cholesterol among patients with depression and diabetes in India: the INDEPENDENT randomized clinical trial. JAMA. 2020;324(7):651–62.

    Article  CAS  PubMed  Google Scholar 

  • Flood D, et al. The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 680 102 adults. Lancet Healthy Longev. 2021;2(6):e340–51. https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(21)00089-1/fulltext.

    Article  PubMed  PubMed Central  Google Scholar 

  • Islek D, Weber MB, Ranjit Mohan A, Mohan V, Staimez LR, Harish R, et al. Cost-effectiveness of a stepwise approach vs standard care for diabetes prevention in India. JAMA Netw Open. 2020;3(7):e207539.

    Article  PubMed  Google Scholar 

  • Manne-Goehler J, Geldsetzer P, Agoudavi K, Andall-Brereton G, Aryal KK, Bicaba BW, et al. Health system performance for people with diabetes in 28 low- and middle-income countries: a cross-sectional study of nationally representative surveys. PLoS Med. 2019;16(3):e1002751.

    Article  PubMed  PubMed Central  Google Scholar 

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Singh, K., Shivashankar, R., Gandral, M., Aravind, L.R., Tandon, N. (2023). Diabetes Management in Asia. In: Rodriguez-Saldana, J. (eds) The Diabetes Textbook. Springer, Cham. https://doi.org/10.1007/978-3-031-25519-9_17

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  • DOI: https://doi.org/10.1007/978-3-031-25519-9_17

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